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Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
BY27 is a potent and selective BET BD2 inhibitor, shows 38, 5, 7, and 21-fold BD1/BD2 selectivity for BRD2, BRD3, BRD4, and BRDT. Anti-cancer activity .
Recombinant endoglycoceramidase I assisted by activator II (rEGCase I assisted by Activator II) is a mixture-form of EGCase I and Activator II. EGCase I is a glycolipid-specific hydrolase that well-suited to a comprehensive analysis of glycosphingolipids (GSLs). Activator II is capable of inducing activity of EGCase without any detergent reagents .
Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium hydrate, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium hydrate improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium hydrate significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
Pantoprazole (sodium) (Standard) is the analytical standard of Pantoprazole (sodium). This product is intended for research and analytical applications. Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
3′-O-N3-dATP (3′-O-Azidomethyl dATP) is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm -1, which determines the DNA sequences continuously .
3′-O-N3-dATP trisodium (3′-O-Azidomethyl dATP trisodium) is the trisodium salt form of 3′-O-N3-dATP. 3′-O-N3-dATP trisodium is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP trisodium acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm -1, which determines the DNA sequences continuously .
MAGL-IN-16 (compound 27) is an oral active, selective and reversible MAGL inhibitor with the IC50 value of 10.3 nM. MAGL-IN-16 can increase the level of 2-AG and shows antidepressant effect in mouse depressed model caused by chronic restraint stress .
Pantoprazole-d6 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].
Pantoprazole-d3 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].
TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss .
N6F11 is a ferroptosis inducer, and can trigger the degradation of glutathione peroxidase 4 (GPX4) specifically in cancer cells. N6F11 can be used for ferroptosis study .
ESI-05 is a specific exchange proteins directly activated by cAMP 2 (EPAC2) inhibitor. ESI-05 inhibits cAMP-mediated EPAC2 GEF activity with an IC50 of 0.43 μM. ESI-05 can be used for the research of diabetes, insulin secretion and neurological disorders .
CD46 Protein serves as a cofactor for complement factor I, safeguarding cells against complement-induced harm. It aids in sperm-oocyte fusion and acts as a T-cell costimulatory factor, facilitating the formation of T-regulatory 1 cells. These cells secrete interleukin-10, suppressing immune responses and preventing autoimmunity. Pathogens can exploit CD46's immune regulation abilities to induce an immunosuppressive state in T-cells. CD46 Protein, Human (HEK293, hFc) is the recombinant human-derived CD46 protein, expressed by HEK293, with C-hFc labeled tag. The total length of CD46 Protein, Human (HEK293, hFc) is 294 a.a., with molecular weight of ~70.0 kDa.
CD160 Protein, present on immune cells, functions as a receptor delivering stimulatory or inhibitory signals, intricately regulating cell activation and differentiation. Existing in GPI-anchored and transmembrane forms, it likely initiates distinct signaling pathways in NK cells and T cells. Acting as a receptor for classical and non-classical MHC class I molecules, it recognizes HLA-C, triggering NK cell cytotoxicity during viral infections. On CD8+ T cells, CD160 binds HLA-A2-B2M, providing costimulation but may inhibit TCR signaling in memory CD8+ T cells during chronic viral infections. Recognizing HLA-G on endothelial cells, CD160 controls angiogenesis. It also participates in bidirectional cell-cell contact signaling with TNFRSF14, modulating immune responses, including anti-tumor responses and bacterial infections. The soluble GPI-cleaved form released by activated lymphocytes might limit lymphocyte effector functions. CD160 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD160 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of CD160 Protein, Human (HEK293, His-Avi) is 134 a.a., with molecular weight of 27-33 kDa.
CD160 Protein, Human (HEK293, Fc) is a recombinant human CD160 expressed in HEK 293 cells with a C-Fc tag at the C-terminus. CD160 Protein binds weakly to MHC I and stimulates NK and CD8+ T‐cell activation.
CDO is an important component of cell surface receptor complexes and plays a key role in promoting intercellular interactions between muscle precursor cells and promoting the differentiation of myogenic cells. This receptor complex includes BOC, CDON, NEO1, cadherin and CTNNB1, which together coordinate complex signaling pathways necessary for cell development. CDO Protein, Human (HEK293, His) is the recombinant human-derived CDO protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CDO Protein, Human (HEK293, His) is 918 a.a., with molecular weight of 120-135 kDa.
CDO is an important component of cell surface receptor complexes and plays a key role in promoting intercellular interactions between muscle precursor cells and promoting the differentiation of myogenic cells. This receptor complex includes BOC, CDON, NEO1, cadherin and CTNNB1, which together coordinate complex signaling pathways necessary for cell development. CDO Protein, Human (963a.a, HEK293, His) is the recombinant human-derived CDO protein, expressed by HEK293 , with C-His labeled tag. The total length of CDO Protein, Human (963a.a, HEK293, His) is 963 a.a., with molecular weight of ~125 kDa.
PTX3 Protein, pivotal in innate pathogen resistance and inflammation regulation, may contribute to self-component clearance and female fertility. As a homooctamer with disulfide-linked structures, PTX3's multifaceted nature maintains immune homeostasis. Interaction with C1q underscores its significance in innate immune responses, positioning PTX3 as a key player in pathogen defense and inflammatory modulation. PTX3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PTX3 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of PTX3 Protein, Mouse (HEK293, His) is 364 a.a., with molecular weight of ~54.0 kDa.
The L1CAM protein is a neural cell adhesion molecule that plays a critical role in cell adhesion dynamics and initiation of tyrosine kinase receptor transmembrane signaling. Its importance spans brain development, affecting processes such as neuronal migration, axonal growth, fasciculations, and synaptogenesis. L1CAM Protein, Human (HEK293, N-His, C-Myc) is the recombinant human-derived L1CAM protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag. The total length of L1CAM Protein, Human (HEK293, N-His, C-Myc) is 1101 a.a., with molecular weight of 150-200 kDa.
The MLANA protein is essential in melanosome biosynthesis, ensuring the stability of GPR143, and plays a key role in the expression, stability, transport, and processing of the melanocyte protein PMEL. Its interaction with PMEL and GPR143 highlights its integral role in the complex network required for second-stage melanosome formation. MLANA Protein, Human (His, B2M) is the recombinant human-derived MLANA protein, expressed by E. coli , with N-His, B2M labeled tag. The total length of MLANA Protein, Human (His, B2M) is 118 a.a., with molecular weight of ~27.2 kDa.
CXCL9 Protein, part of the intercrine alpha family, is essential for chemokines crucial in intercellular communication and immune responses. Within this family, CXCL9 likely plays a key role in modulating inflammatory processes and influencing cellular interactions. Further investigation is essential to reveal specific functions and implications within the broader chemokine CxC family, emphasizing its significance in mediating immune responses while adhering to production methods. Animal-Free CXCL9 Protein, Pig (His) is the recombinant pig-derived animal-FreeCXCL9 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free CXCL9 Protein, Pig (His) is 104 a.a., with molecular weight of ~12.88 kDa.
CXCL9, also known as MIG, is one member of the ELR-negative CXC chemokine subfamily, and can be induced by IFN-γ. CXCL9 binds to its receptor CXCR3 and can recruit CXCR3+ cells, such as effector T cells, regulatory T cells (Tregs) and CD8+ cytotoxic T cells. CXCL9 is involved in immunoregulatory and inflammatory processes, but it also play a key role in tumor growth, angiogenesis, and metastasis. MIG/CXCL9 Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 105amino acids (T22-T126).
rHuEukaryotic translation initiation factor 4E-binding protein 1/EIF4EBP1, His; Eukaryotic Translation Initiation Factor 4E-Binding Protein 1; 4E-BP1; eIF4E-Binding Protein 1; Phosphorylated Heat- and Acid-Stable Protein Regulated BY Insulin 1; PHAS-I; EIF4EBP1
EIF4EBP1 is a translation initiation repressor protein that complexly regulates EIF4E activity. In the hypophosphorylated state, EIF4EBP1 competes with EIF4G1/EIF4G3 to inhibit translation by binding to EIF4E. EIF4EBP1 Protein, Human (His) is the recombinant human-derived EIF4EBP1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of EIF4EBP1 Protein, Human (His) is 118 a.a., with molecular weight of ~17.0 kDa.
TFF1; BCEI; D21S21; HP1.A; HPS2; pNR-2; pS2; trefoil factor 1; gastrointestinal trefoil protein pS2; breast cancer estrogen-inducible sequence; Breast cancer estrogen-inducible protein; breast cancer, estrogen-inducible sequence expressed in gastrointestinal trefoil protein pS2; pS2 protein; trefoil factor, BCE1, human pS2 induced BY estrogen from human breast cancer cell line M
TFF1 protein acts as an endogenous repressor of isoform 1 and interacts with CHK1, antagonizing its function and promoting the transition from the S to G2/M phase of the cell cycle. TFF1 Protein, Human (P. pastoris, N-His) is the recombinant human-derived TFF1 protein, expressed by P. pastoris, with N-6*His labeled tag. The total length of TFF1 Protein, Human (P. pastoris, N-His) is 60 a.a., with molecular weight of 8.7 kDa.
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of EpCAM/TROP1 Protein, Human (His-SUMO) is 242 a.a., with molecular weight of ~40.4 kDa.
Pantoprazole-d6 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].
Pantoprazole-d3 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].
Antigen identified BY monoclonal antibody Ki 67; Antigen KI67; KIA; Ki67; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_MOUSE.
WB; ELISA; IHC-P; IHC-F; Flow-Cyt; ICC; IF
Human, Mouse,
Ki-67 Antibody is an unconjugated, approximately 358 kDa, rabbit-derived, anti-Ki-67 polyclonal antibody. Ki-67 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, background without labeling.
EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated BY insulin 1; PHAS-I
WB, IHC-P, IP
Human, Mouse, Rat, Hamster
4E BP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 13 kDa, targeting to 4E BP1. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.
MIG; CMK; C-X-C motif chemokine 9; CXCL9; chemokine (C-X-C motif) ligand 9; crg-10; Humig; monokine induced BY gamma interferon; SCYB9; Small inducible cytokine B9; small inducible cytokine subfamily B member 9.
ELISA; IHC-P; IHC-F; IF
Human, Mouse(predicted: Rat, Pig, Cow, Horse)
CXCL9 Antibody is an unconjugated, approximately 14 kDa, rabbit-derived, anti-CXCL9 polyclonal antibody. CXCL9 Antibody can be used for: ELISA, IHC-P, IHC-F, IF expriments in human, mouse, and predicted: rat, pig, cow, horse background without labeling.
EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated BY insulin 1; PHAS-I
WB, IHC-P, IP
Human, Mouse, Rat
Phospho-4E BP1 (Thr46) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 13 kDa, targeting to Phospho-4E BP1 (Thr46). It can be used for WB,IHC-P,IP assays with tag free, in the background of Human, Mouse, Rat.
